The Stepwise Alkylation of an Ester by the Grignard Method
Chemistry, stepwise alkylation, ester, grignard method
Chemistry | Physical Sciences and Mathematics
In 1849, Frankland prepared the first organometallic compound. He was seeking to produce the free ethyl radical from ethyl iodide by using zinc to remove the iodine. Instead of the free radical he produced diethyl zinc.
2 C2H5I + 2 Zn --> (C2H5)2Zn + ZnI2
His further investigations with these organometallic compounds laid the ground work for the later advances in this field.
Department 1 Awarding Honors Status
Leiby Jr., G. M. (1957). The Stepwise Alkylation of an Ester by the Grignard Method (Undergraduate honors thesis, University of Redlands). Retrieved from https://inspire.redlands.edu/cas_honors/261