The Inhibition of the Growth of Cancer Cells by the Modified Mandelo Nitrite β-Gentiobioside Molecule
Biology, cancer, molecule, mandelo nitrite, gentiobioside, chemotherapy
Cancer Biology | Cell and Developmental Biology | Life Sciences
In the normal cell the enzyme, rhodanese, detoxifies mandelo nitrite β-gentiobiosite into thicyanate. In those cancer cells which lack rhodanese, the enzyme, β-glucosidase, hydrolyses mandelo nitrite β-gentiobioside into glucose, ben zaldehyde, and cyanide. The cyanide released by the enzymatic mechanism destroys the cell. This is sufficient grounds for an investigation and analysis of the molecule as a chemotherapeutic agent in the treatment of Cancer.
Department 1 Awarding Honors Status
Maxwell, T. L. (1976). The Inhibition of the Growth of Cancer Cells by the Modified Mandelo Nitrite β-Gentiobioside Molecule (Undergraduate honors thesis, University of Redlands). Retrieved from https://inspire.redlands.edu/cas_honors/384