Copper, Vanadium, Platinum, Palladium, Hydrolysis, Complexation Reactions
Biochemistry | Inorganic Chemistry | Medical Biochemistry
Copper, Vanadium, Platinum, and Palladium metal complexes were synthesized through coordination with N-(2-aminophenlo)-1-methyl-2-imidazole carbozaldeimine, a Schiff-base ligand. These metal complexes were characterized through the use of elemental analysis, UV-vis spectroscopy, and IR spectroscopy. Elemental analysis data determined that the proposed structure of the Cu(II) complex was not correct. The mass percent values did not fall within 5% of the values calculated from the proposed structure. No possible structures could be deduced from the experimental data. IR spectroscopic data showed a shift in the imine peak of the coordinated ligand from 1634 cm-1 to1625.7 cm-1indicating strong coordination through the imine nitrogen to the metal atom. Furthermore, the IR spectrum of the Zn(II) complex shows a disappearance fo the broad bend assigned to the OH group in the ligand, indicating coordination through the phenolic oxygen of the ligand. The Cu(II), V(IV), Pt(II), Pt(IV), and Pd(II) complexes failed to show such indicative shifts in their IR spectra, thus their coordination patterns cannot be determined x-ray crystallographic data. Hydrolytic studies were conducted in order to determine if these metal complexes were capable of cleaving phosphodiester bonds. The results of these studies were inconclusive and require further study. The Cu(ii) and Pt(II) complexes showed hydrolytic activity, but these studies were difficult to reproduce. A possible explanation is the lack of true catalytic activity of these complexes.
Department 1 Awarding Honors Status
Walker, C. H. (2008). Synthesis of Metal Complexes for Hydrolysis of Phosphodiester Bonds (Undergraduate honors thesis, University of Redlands). Retrieved from https://inspire.redlands.edu/cas_honors/51
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