The Buoyant Properties of Synthetic and Natural Polypeptides
polypeptides, buoyancy, synthetic, amino acid, homopolypeptides
Biology | Cell and Developmental Biology | Life Sciences | Medicine and Health Sciences
The buoyant behavior of six reactive-group homopolypeptides (i.e. synthetic polypeptides which are constructed from a single type of amino acid which is ionizable in aqueous solution) is examined in CsCl as a function of pH in the analytical ultracentrifuge, by the method of establishing sedimentation equilibrium in a density gradient. The homopolypeptides studied are poly-L-glutamic acid(b) (P-Glu), poly-L-aspartic acid (P-Asp), poly-L-lysine hydrobromide (P-Lys), poly-L-histidine (P-His), poly-L-tyrosine (P-Tyr), and poly-L-arginine hydrochloride (P-Arg).
Zilius, J. S. (1968). The Buoyant Properties of Synthetic and Natural Polypeptides (Undergraduate honors thesis, University of Redlands). Retrieved from https://inspire.redlands.edu/cas_honors/806