A Study of The Uncatalyzed Thermal Prins Reaction With Formaldehyde and l-Dodecene
chemistry, uncatalyzed thermal prins reaction, formaldehyde, aldehyde, alkene, prins reaction
Chemistry | Physical Sciences and Mathematics
The reaction of an aldehyde with an alkene was first reported by Kriewitz. In 1889 he found that the reaction of Paraformaldehyde on a pinene produced unsaturated alcohols.
Prins, in 1917, was the first to carry out a comprehensive study of the reaction of Formaldehyde with alkenes. H found that the formals of 1,3-diols or unsaturated alcohols were produced in aqueous medium, and that the corresponding acetates were produced when the reactions were performed in acetic acid medium. Because of his early and comprehensive work, the reactions of aldehydes with alkenes is known as the Prins reaction.
Sutherland, J. D. (1967). A Study of The Uncatalyzed Thermal Prins Reaction With Formaldehyde and l-Dodecene (Undergraduate honors thesis, University of Redlands). Retrieved from https://inspire.redlands.edu/cas_honors/838