Document Title

Association of Dry Cow Therapy with the Antimicrobial Susceptibility of Fecal Coliform Bacteria in Dairy Cows

Department/School

Biology

Abstract

The prophylactic use of intramammary antimicrobial drugs at the end of lactation in dairy cows, known as dry cow therapy (DCT), is widely practiced in US dairy herds. This extremely common use of high-dose, slow-release antimicrobials may influence the ecology of bacterial flora on dairy farms. We investigated the association between the antimicrobial used for intramammary DCT and the relative number of fecal coliform bacteria with reduced susceptibility to three antimicrobial drugs in dairy cattle. Most probable number (MPN) data were estimated from 463 individual fecal samples collected from lactating cows in 15 dairy herds in Ohio, USA. These data were used to calculate the relative number of fecal coliform bacteria with reduced susceptibility to cephalothin, streptomycin, and tetracycline for individual cow samples. The farms included in this project were classified based on DCT, with 8 farms using a cephalosporin-based product and the remaining 7 using a penicillin/streptomycin therapy. Results of a linear mixed model indicate that herds using a cephalosporin DCT had higher (P

Document Type

Article

Publication Title

Preventive Veterinary Medicine

Publication Date

8-1-2010

Volume

96

Issue

1-2

Pages

30-35

Digital Object Identifier (DOI)

10.1016/j.prevetmed.2010.05.014

PubMed ID (PMID)

20573412

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